Thermo Scientific™ Pierce™ TMT11plex Yeast Digest Standard, 20 µg

Thermo Scientific™ Pierce™ TMT11plex Yeast Digest Standard, 20 µg

The Thermo Scientific Pierce TMT11plex Yeast Digest Standard is a lyophilized yeast peptide mixture of four congenic strains labeled with TMT11plex reagents to monitor LC-MS/MS system performance for Tandem Mass Tag (TMT) quantitation.

Quantitative proteomic strategies using TMT reagents enable sample multiplexing and precise measurement of protein abundance. However, successful execution of this workflow includes multiple steps that may require optimization, including chromatography, mass spectrometry (MS), and data analysis. A critical parameter for success in this workflow is the ability to consistently detect the TMT fragment ions across the 11 channels of multiplexing. This standard has been specifically designed as a tool to monitor LC-MS/MS system performance for TMT quantitation and MS method optimization and validation.

For use with: Mass Spectrometer

Features

• Convenient—pre-labeled with TMT11plex reagents in a ready-to-use lyophilized format
• Highly validated—yeast strains verified for genotype, equimolar mixing of the TMT-labeled strains, and overall protein quantitation using TMT
• Diagnostic—excellent QC assay tool for quality assessment of LC and MS instrument status
• Quantitative—designed to measure the quantitative precision of the TMT reporter ions for each of the 11 channels