Thermo Scientific™ POROS™ Oligo (dT)25 Affinity Resin, 5000 mL
On demand
Order number :
A47385
Thermo Scientific™ POROS™ Oligo (dT)25 Affinity Resin, 5000 mL
POROS Oligo (dT)25 Affinity Resin is designed for the purification and isolation of mRNA from in vitro transcription (IVT) manufacturing processes. The resin effectively separates mRNA from components of the transcription reaction process, such as enzymes and plasmid DNA.
POROS Oligo (dT)25 Affinity Resin was developed to address the selectivity and capacity requirements for large-scale downstream purification of a range of mRNA constructs used in vaccine and gene therapy applications. Unlike alternate approaches, the resin selectively captures the mRNA via the polyadenylated (polyA) tail using simple salt and water purification steps.
Features
- Easy mRNA purification from crude transcription mix to effectively remove plasmid DNA and other IVT components
- Simplified workflow helps to maximize efficiency, thereby reducing complexity of subsequent polish steps
- Excellent scalability
- Non-animal derived
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