1p \ 19q, (FISH)

Detection of 19q13 \ 1p36 Co-deletions 

Main indication:

GBM.

Test usage:

Deletions of chromosome 1p and 19q arms are frequent genetic abnormalities in primary human gliomas and are especially common in oligodendrogliomas. While 1p deletions are relatively common in other types of tumors, 19q deletions appear to be common only in gliomas. These deletions have been associated with a favorable response to chemotherapy with long survival.