EWSR1, (FISH)
On demand
Order number :
ST-F08
Detection of 22q12 translocations
Main indication:
Ewing Sarcoma.
Test usage:
This test detects rearrangements involving the EWSR1 gene region (22q12) via fluorescence in situ hybridization (FISH) in formalin-fixed, paraffin-embedded tissue specimens. FISH is performed to qualitatively assess for the presence of EWSR1 translocations that occur in soft tissue tumors including Ewing sarcoma/peripheral neuroectodermal tumor, desmoplastic small round cell tumor, clear cell sarcoma, angiomatoid fibrous histiocytoma, extraskeletal myxoid chondrosarcoma, and myxoid liposarcoma. Testing for EWSR1 gene rearrangement may aid in the diagnosis of these tumors.