Breast Cancer Panel NGS library preparation Kit

Breast Cancer Panel NGS library preparation Kit

Cancer is a type of diseases caused by accumulation of genetic changes, which results in abnormal cell growth and invasive behaviors that potentially spread to other body parts. Most common nucleotide sequence changes in cancer involve single-nucleotide variants and small insertions or deletions.

Breast cancer is a type of cancer that occurs when cells in breast mutate and keep reproducing. It is one of the most common cancer types and one of the leading causes of cancer death among women. About 12% women in the United States will develop breast cancer in her lifetime. Atila Breast Cancer Panel NGS library preparation Kit targets 139 amplicon regions of 16 breast cancer related genes, including AKT1, BAP1, BRCA1, BRCA2, BRIP1, CCND1, CHEK2, EP300, ERBB2, GATA3, MAP2K4, PALB2, PBRM1, PIK3CA, RB1, and TP53 etc. The resulting sample library is compatible with Illumina NGS sequencing. The current method employs novel primer design strategies, greatly simplifies sample preparation procedures, and enables rapid screening and discovering genetic variations.

Features

• High sensitivity: The kit can use as low as 100pg purified DNA.
• Short preparation time: Sample library is ready within 2.5-3 hours.
• Simple procedures: Hands-on time is as short as 30 minutes.
• High specificity: high on target rate and high uniformity.