Invitrogen 25 mg CD140b (PDGFRB) Monoclonal Antibody (APB5), Functional Grade, eBioscience™
On demand
Order number :
16-1402-025
Invitrogen 25 mg CD140b (PDGFRB) Monoclonal Antibody (APB5), Functional Grade, eBioscience™
The APB5 monoclonal antibody reacts with the mouse CD140b molecule, the beta chain of the platelet derived growth factor receptor (PDGF receptor). PDGFRb is a receptor tyrosine kinase that forms dimers on the surface upon ligand binding and phosphorylates substrates. Dimers of PDGFR consist of either homodimers of alpha/alpha, beta/beta, or heterodimers of alpha/beta and serve as a substrate for its kinase activity. CD140b is expressed by embryonic tissues and mesenchymal-derived cells of the adult mouse tissues. The PDGFR beta chain is reported to play a significant role in formation of fibrous atherosclerotic lesions.
- Filtration: 0.2 µm post-manufacturing filtered.
- Purity: Greater than 90%, as determined by SDS-PAGE.
- Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by LAL assay.
- Aggregation: Less than 10%, as determined by HPLC.
- Applications: Neutralization (Neu), Functional Assay (FN).
- Recommended Isotype Control: Rat IgG2a kappa Isotype Control (eBR2a), Functional Grade, eBioscience™.
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