Invitrogen CD11c Monoclonal Antibody (N418), Alexa Fluor 532, 100 µg, eBioscience™

Invitrogen CD11c Monoclonal Antibody (N418), Alexa Fluor 532, 100 µg, eBioscience™

The N418 monoclonal antibody reacts with mouse CD11c, the integrin alphaX. CD11c non-covalently associates with beta2 integrin to form the CD11c/CD18 heterodimer. CD11c is expressed by dendritic cells, a subset of Intestinal Intraepithelial Lymphocytes (IEL) and some activated T cells. CD11c/CD18 binds to CD54, iC3b and fibrinogen and plays a role in leukocyte adhesive interactions. N418 binds to CD11c on splenic dendritic cells in the T-dependent areas of mouse spleen and precipitates a 150, 90 kDa heterodimer.

• Alexa Fluor® 532 is excited with the Green laser (532 nm) and emits at 561 nm. This cannot be used with the Yellow-Green laser (561 nm). We recommend using a 560/14 band pass filter. Please make sure that your instrument is capable of detecting this fluorochome.
• Recommended Isotype Control: Armenian Hamster IgG Isotype Control (eBio299Arm), Alexa Fluor 532, eBioscience™.