Invitrogen™ LentiArray™ Human Apoptosis CRISPR Library

Invitrogen™ LentiArray™ Human Apoptosis CRISPR Library

The award-winning Invitrogen™ LentiArray™ Human Apoptosis Library targets 904 genes with up to 4 gRNA per gene target (pooled in a single well) for a total of 3,616 gRNAs. Libraries are delivered as 100 μL of ready to use lentiviral particles per gene target with an average titer of 1x108 TU/mL (functional titer determined by antibiotic resistance) and are also available as glycerol stocks.

Apoptosis is a tightly regulated process that is essential for maintaining homeostasis in multicellular organisms. Inhibition of apoptosis can result in the development of cancer, autoimmune, and inflammatory disease and is involved in viral infection. Conversely, over-activation of apoptosis can lead to atrophy, tissue damage, and neurodegenerative disease. The gene targets within this library were selected using the most up-to-date genome databases, including the NCBI RefSeq database, and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC).

Contents

• 1 library set, 100 µL/target