Invitrogen™ LentiArray™ Human Ion Channel CRISPR Library

Invitrogen™ LentiArray™ Human Ion Channel CRISPR Library

The award-winning Invitrogen™ LentiArray™ Human Ion Channel Library targets 328 genes with up to 4 gRNA per gene target (pooled in a single well) for a total of 1,312 gRNAs. Libraries are delivered as 100 μL of ready to use lentiviral particles per gene target with an average titer of 1x108 TU/mL (functional titer determined by antibiotic resistance) and are also available as glycerol stocks.

Ion channels are integral membrane proteins that establish the electrochemical gradient that gives rise to both the resting membrane potential and the formation of action potentials which are crucial to nerve conduction and heart and muscle contraction, as well as other processes such as insulin release and activation of T-cells. The gene targets within this library were selected using the most up-to-date genome databases, including the NCBI RefSeq database, and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC).

Contents

• 1 library set, 100 µL/target