Invitrogen™ LentiArray™ Human Protease CRISPR Library

Invitrogen™ LentiArray™ Human Protease CRISPR Library

The award-winning Invitrogen™ LentiArray™ Human Protease Library targets 475 genes with up to 4 gRNA per gene target (pooled in a single well) for a total of 1,900 gRNAs. Libraries are delivered as 100 μL of ready to use lentiviral particles per gene target with an average titer of 1x108 TU/mL (functional titer determined by antibiotic resistance) and are also available as glycerol stocks.

Proteases degrade proteins but are also integral signaling molecules, and the deregulation of protease signaling pathways has been implicated in the development of cardiovascular disease, neurological disorders, cancer, and inflammatory disease. The gene targets within this library were selected using the most up-to-date genome databases, including the NCBI RefSeq database, and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC).

Contents

• 1 library set, 100 µL/target