Invitrogen PDI Monoclonal Antibody (RL90), Alexa Fluor 647
On demand
Order number :
MA3-019-A647
Invitrogen PDI Monoclonal Antibody (RL90), Alexa Fluor 647
Protein disulfide isomerase (PDI) is a multifunctional protein that catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, the protein seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. It may therefore cause structural modifications of exofacial proteins. Inside the cell, PDI seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, it functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, it facilitates aggregation (anti-chaperone activity).
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