Invitrogen™ Silencer™ Human Cell Cycle Regulation siRNA Library

Invitrogen™ Silencer™ Human Cell Cycle Regulation siRNA Library

Proteins that regulate cell division are crucial for controlling cell growth and are therefore potentially important drug targets. The Silencer™ Human Cell Cycle Regulation siRNA Library includes 4,398 Ambion™ Silencer siRNAs targeting 1,466 genes. These siRNA gene targets include cyclin-dependent kinases, or CDKs, which are crucial for cell cycle progression, regulators of cell cycle progression such as CIP/KIP family proteins and members of the INK4 family of cell cycle inhibitors, proteins in the retinoblastoma family, and DNA replication factors such as the cell division cycle proteins (CDCs). The library was designed using the most up-to-date genome databases, including the NCBI RefSeq database and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC). Utilizing Ambion Silencer technology built on stringent bioinformatics to enable high target specificity and siRNA potency, the Silencer Human Cell Cycle Regulation siRNA Library is an ideal solution for focused and cost-effective RNAi screening against cell cycle regulation.

Features

• Comprehensive—Expedite functional gene discovery with pre-defined Silencer Human GPCR siRNA Library
• Reliable—Increase target screening accuracy with three individual siRNAs per gene target
• Effective—Reduce off target impacts at low concentrations with proven Ambion Silencer siRNA design
• Convenient—Reduce data de-convolution and accelerate target validation with our arrayed format
• Customizable—Choose the best option for your workflow demands, including additional siRNA scales and pooled formats

Contents

• 4398 total siRNAs targeting 1466 genes plated onto 96-well plates (51 plates)