Invitrogen™ Silencer™ Human Tumor Suppressor siRNA Library

Invitrogen™ Silencer™ Human Tumor Suppressor siRNA Library

Mutations that cause a loss or reduction in gene function can result in the progression to cancer, usually in combination with other genetic changes. Tumor suppressor genes, or anti-oncogenes, can protect cells on the path to becoming cancerous. The Silencer™ Human Tumor Suppressor siRNA Library contains 2,175 Ambion™ Silencer siRNAs targeting 725 tumor suppressor genes. The library was designed using the most up-to-date genome databases, including the NCBI RefSeq database and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC) as well as the Tumor Suppressor Gene Database (TSGene). Utilizing Ambion Silencer technology built on stringent bioinformatics to enable high target specificity and siRNA potency, the Silencer Human Tumor Suppressor siRNA Library is an ideal solution for focused and cost-effective RNAi screening against tumor suppressor genes

Features

• Comprehensive—Expedite functional gene discovery with pre-defined Silencer Human GPCR siRNA Library
• Reliable—Increase target screening accuracy with three individual siRNAs per gene target
• Effective—Reduce off target impacts at low concentrations with proven Ambion Silencer siRNA design
• Convenient—Reduce data de-convolution and accelerate target validation with our arrayed format
• Customizable—Choose the best option for your workflow demands, including additional siRNA scales and pooled formats

Contents

• 2175 total siRNAs targeting 725 genes plated onto 96-well plates (27 plates)