Invitrogen™ Silencer™ Human Cell Surface siRNA Library

Invitrogen™ Silencer™ Human Cell Surface siRNA Library

Cell surface receptors are specialized integral membrane proteins that take part in communication between the cell and its surroundings. Extracellular signaling molecules, typically hormones, neurotransmitters, cytokines, growth factors and cell recognition molecules, attach to the receptor, triggering changes in the function of the cell. The Silencer™ Human Cell Surface siRNA Library contains 2,367 Ambion™ Silencer siRNAs targeting 789 genes. This library was designed using the most up-to-date genome databases, including the NCBI RefSeq database and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC). Utilizing Ambion Silencer technology built on stringent bioinformatics to enable high target specificity and siRNA potency, the Silencer Human Cell Surface siRNA Library is an ideal solution for focused and cost-effective RNAi screening against cell surface-based signaling.

Features

• Comprehensive—Expedite functional gene discovery with pre-defined Silencer Human GPCR siRNA Library
• Reliable—Increase target screening accuracy with three individual siRNAs per gene target
• Effective—Reduce off target impacts at low concentrations with proven Ambion Silencer siRNA design
• Convenient—Reduce data de-convolution and accelerate target validation with our arrayed format
• Customizable—Choose the best option for your workflow demands, including additional siRNA scales and pooled formats

Contents

• 2367 total siRNAs targeting 789 genes plated onto 96-well plates (27 plates)