Invitrogen™ Silencer™ Human Kinase siRNA Library

Invitrogen™ Silencer™ Human Kinase siRNA Library

Given their importance in cell signaling and many other biological pathways, kinases have become key drug targets. The Silencer™ Human Kinase siRNA Library contains 2,127 Ambion™ Silencer siRNAs targeting 709 human kinase genes for performing RNAi screens against the kinome. This siRNA library is designed using the most up-to-date genome databases, including the NCBI RefSeq database and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC) as well as additional resources, such as the KinBase database. Utilizing Ambion Silencer technology built on stringent bioinformatics to enable high target specificity and siRNA potency, the Silencer Human Kinase siRNA Library allows accurate yet cost-effective RNAi screening for kinase signaling pathways.

Features

• Comprehensive—Expedite functional gene discovery with pre-defined Silencer Human Kinase siRNA Library
• Reliable—Increase target screening accuracy with three individual siRNAs per gene target
• Efficient—Reduce off target impacts at low concentrations with proven Ambion Silencer siRNA design
• Convenient—Reduce data de-convolution and accelerate target validation with our arrayed format
• Customizable—Choose the best option available for your workflow demands, including additional siRNA scales and pooled formats

Contents

• 2127 total siRNAs targeting 709 genes plated onto 96-well plates (27 plates)