Invitrogen™ Silencer™ Human GPCR siRNA Library

Invitrogen™ Silencer™ Human GPCR siRNA Library

G-protein–coupled receptors (GPCRs) are key components of many signal transduction pathways and also represent an important class of druggable genes. The Silencer™ Human GPCR siRNA Library targets 1,134 Ambion™ Silencer siRNAs representing 378 non-olfactory human GPCRs. This library is designed using the most up-to-date genome databases, including the NCBI RefSeq database and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC). Utilizing Ambion Silencer technology built on stringent bioinformatics to enable high target specificity and siRNA potency, the Silencer Human GPCR siRNA Library allows accurate yet cost-effective RNAi functional screening against known GPCRs.

Features

• Comprehensive—Expedite functional gene discovery with pre-defined Silencer Human GPCR siRNA Library
• Reliable—Increase target screening accuracy with three individual siRNAs per gene target
• Effective—Reduce off target impacts at low concentrations with proven Ambion Silencer siRNA design
• Convenient—Reduce data de-convolution and accelerate target validation with our arrayed format
• Customizable—Choose the best option for your workflow demands, including additional siRNA scales and pooled formats

Contents

• 1134 total siRNAs targeting 378 genes plated onto 96-well plates (15 plates)