Invitrogen™ Silencer™ Human Ion Channel siRNA Library

Invitrogen™ Silencer™ Human Ion Channel siRNA Library

Ion channels are key components in a multitude of biological processes, including rapid changes in muscle cell contractions, epithelial transport of nutrients and ions, T cell activation and pancreatic beta-cell insulin release. They are therefore a frequent target for drug discovery. The Silencer™ Human Ion Channel siRNA Library contains 1,011 Ambion™ Silencer siRNAs targeting 337 genes. The library was designed using the most up-to-date genome databases, including the NCBI RefSeq database and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC). Utilizing Ambion Silencer technology built on stringent bioinformatics to ensure high target specificity and siRNA potency, the Silencer Human Ion Channel siRNA Library is an ideal solution for focused and cost-effective RNAi screening against ion channel gene knockdown studies.

Features

• Comprehensive—Expedite functional gene discovery with pre-defined Silencer Human GPCR siRNA Library
• Reliable—Increase target screening accuracy with three individual siRNAs per gene target
• Effective—Reduce off target impacts at low concentrations with proven Ambion Silencer siRNA design
• Convenient—Reduce data de-convolution and accelerate target validation with our arrayed format
• Customizable—Choose the best option for your workflow demands, including additional siRNA scales and pooled formats

Contents

• 1011 total siRNAs targeting 337 genes plated onto 96-well plates (12 plates)