Invitrogen™ Silencer™ Human Transcription Factor siRNA Library

Invitrogen™ Silencer™ Human Transcription Factor siRNA Library

Transcription factors are fast becoming promising drug targets, as they bind to and regulate the transcription of genes. The Silencer Human Transcription Factor siRNA Library targets genes expressing proteins that bind DNA in a sequence-specific manner to control the rate of transcription of genetic information from DNA to messenger RNA. The Silencer™ Human Transcription Factor siRNA Library contains a total of 5,583 Ambion™ Silencer siRNAs targeting 1,861 genes. The library was designed using the most up-to-date genome databases, including the NCBI RefSeq database and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC). Utilizing Ambion Silencer technology built on stringent bioinformatics to ensure high target specificity and siRNA potency, the Silencer Human Transcription Factor siRNA Library is an ideal solution for focused and cost-effective transcription factor RNAi screening.

Features

• Comprehensive—Expedite functional gene discovery with pre-defined Silencer Human GPCR siRNA Library
• Reliable—Increase target screening accuracy with three individual siRNAs per gene target
• Effective—Reduce off target impacts at low concentrations with proven Ambion Silencer siRNA design
• Convenient—Reduce data de-convolution and accelerate target validation with our arrayed format
• Customizable—Choose the best option for your workflow demands, including additional siRNA scales and pooled formats

Contents

• 5583 total siRNAs targeting 1861 genes plated onto 96-well plates (66 plates)