Invitrogen™ Silencer™ Select Human Apoptosis siRNA Library

Invitrogen™ Silencer™ Select Human Apoptosis siRNA Library

The Silencer™ Select Human Apoptosis siRNA Library provides investigators with a focused siRNA screening platform targeting apoptosis genes and enabling a detailed analysis of the apoptotic signaling pathway. The Silencer Select Human Apoptosis siRNA Library contains 2,772 Ambion™ Silencer Select highly potent and chemically-modified siRNAs targeting 924 apoptosis genes. This library was designed using the most up-to-date genome databases, including the NCBI RefSeq database and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC). The Silencer Select siRNAs are designed using Thermo Fisher Scientific’s leading design algorithms—along with our novel locked nucleic acid (LNA) chemical modifications, this helps to maximize the efficacy, specificity and potency required for confident RNAi screens during apoptosis investigations

Features

• Superior efficacy—Reduce off target effects by up to 90% due to latest design algorithms and LNA chemical modifications
• Highest efficiency—Perform knockdown studies with 100-fold more potent siRNAs than currently available siRNAs
• Dependable—Achieve faster discoveries via consistency of gene knockdown and reliability of phenotypic results
• Convenient—Reduce data de-convolution and accelerate target validation with our arrayed format
• Customizable—Choose the best option for your workflow demands, including additional siRNA scales and pooled formats

Contents

• 2772 total siRNAs targeting 924 genes plated onto 96-well plates (33 plates)