MDM2 Gene Amplification Probe Detection Kit (IVD)
On demand
Brand origin :
China
Expiry time :
On demand
Delivery time :
1 Week/s
Delivery cost :
On demand
Unit size :
10 Tests
Order number :
FP-054
MDM2 Gene Amplification Probe Detection Kit (IVD)
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.
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