Thermo Scientific™ AMAS (N-α-maleimidoacet-oxysuccinimide ester)
On demand
Order number :
22295
Thermo Scientific™ AMAS (N-α-maleimidoacet-oxysuccinimide ester)
Thermo Scientific Pierce AMAS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a very short spacer arm (4.4 angstroms).
Features
- Reactive groups: NHS ester and maleimide
- Reactive towards: amino and sulfhydryl groups
- Shortest of aliphatic spacer series which includes AMAS, BMPS, GMBS and EMCS
- NHS ester end couples with primary amines at pH 7-9, forming stable amide bonds
- Maleimide reacts with -SH groups at pH 6.5-7.5, forming stable thioether linkages
- Non-cleavable
- Water-insoluble (dissolve first in DMF or DMSO)
- Very short aliphatic spacer has low potential for eliciting an immune response
There are no specifications
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