Thermo Scientific™ Pierce™ Hydroxylamine-HCl
On demand
Order number :
26103
Thermo Scientific™ Pierce™ Hydroxylamine-HCl
Thermo Scientific Pierce Hydroxylamine-HCl has many uses, which include cleaving Asn-Gly peptide bonds and deprotecting (exposing) sulfhydryls on SATA-modified molecules for conjugation.
Hydroxylamine·HCl is a strong reducing agent that is useful in biochemical crosslinking applications, including the deacetylation of SATA and chemical cleavage of EGS and Sulfo-EGS. Hydroxylamine converts carbonyl compounds (aldehydes and ketones) to their oxime derivatives in the presence of a weak base. Therefore, crosslinkers and other compounds that contain a carbonyl within their structure are cleavable with hydroxylamine·HCl.
Features
- Quench amine-labeling or crosslinking reactions (e.g., with NHS esters)
- Expose protected sulfhydryl groups on SATA-modified molecules
- Cleave carbonyl-containing crosslinkers such as EGS and Sulfo-EGS
There are no specifications
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