Thermo Scientific™ CaptureSelect™ Biotin Anti-Free LC-kappa (Human) Conjugate, 500 µg

Thermo Scientific™ CaptureSelect™ Biotin Anti-Free LC-kappa (Human) Conjugate, 500 µg

CaptureSelect™ Biotin Anti-Free LC-kappa (Hu) Conjugate consists of a 13 kDa llama antibody fragment (affinity ligand) that binds highly selectively to free human kappa light chains and dimers thereof. The functionality is based on recognition of an epitope on the human CL-kappa domain that is masked in intact antibodies and Fab fragments. The affinity ligand is chemically conjugated to biotin via an appropriate spacer that retains the binding reactivity of the ligand when used in combination with streptavidin-based conjugates or streptavidin pre-coated surfaces.

Features

• Detect, quantitate, and characterize free human kappa light chains in (crude) antibody preps
• Avoid cross-binding with human kappa light chains present in intact and properly folded antibodies and Fab fragments of any human antibody isotype such as IgG, IgA, IgM, IgD, and IgE