Thermo Scientific™ DMS (dimethyl suberimidate)
On demand
Order number :
20700
Thermo Scientific™ DMS (dimethyl suberimidate)
Thermo Scientific Pierce DMS is dimethyl suberimidate, a membrane-permeable crosslinker that contains an amine-reactive imidoester group at each end of an 8-atom spacer arm.
Features
- Reactive groups: imidoester (both ends)
- Reactive towards: amino groups (primary amines)
- Longest of three similar imidoester crosslinkers, which include DMA, DMP and DMS
- Water-soluble
- Imidoesters react with amines at alkaline pH values (pH 8-10) to form amidine bond
- Amidine bond retains net charge character of protein primary amine to which it reacts
- Reversible at high pH values
- Tool for study of quarternary structure of proteins
There are no specifications
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