Thermo Scientific™ DMP (dimethyl pimelimidate), 50 mg

Thermo Scientific™ DMP (dimethyl pimelimidate), 50 mg

Thermo Scientific Pierce DMP is dimethyl pimelimidate, a membrane-permeable crosslinker that contains an amine-reactive imidoester group at each end of a 7-atom spacer arm.

Features

• Reactive groups: imidoester (both ends)
• Reactive towards: amino groups (primary amines)
• Mid-length reagent of three similar imidoester crosslinkers, which include DMA, DMP and DMS
• Water-soluble
• Imidoesters react with amines at alkaline pH values (pH 8-10) to form amidine bond
• Amidine bond retains net charge character of protein primary amine to which it reacts
• Reversible at high pH values
• Tool for study of quarternary structure of proteins