Thermo Scientific™ LC-SMCC (succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxy-(6-amidocaproate))
On demand
Order number :
22362
Thermo Scientific™ LC-SMCC (succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxy-(6-amidocaproate))
Thermo Scientific Pierce LC-SMCC is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a long cyclohexane-stabilized spacer arm (16.2 angstroms).
Features
- Reactive groups: NHS ester and maleimide
- Reactive toward: amino and sulfhydryl groups
- Long-chain variety of SMCC
- High purity, crystalline reagent can be used to create high-purity maleimide-activated derivatives
- Non-cleavable
- Water-insoluble (dissolve first in DMF or DMSO)
- Cyclohexane bridge confers added stability to the maleimide group making LC-SMCC an ideal crosslinking agent for maleimide activation of proteins. Maleimide groups are stable for 64 hours in 0.1 M sodium phosphate buffer, pH 7 at 4°C.
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