Thermo Scientific™ Pierce™ Sulfhydryl Addition Kit
On demand
Order number :
23460
Thermo Scientific™ Pierce™ Sulfhydryl Addition Kit
The Thermo Scientific Pierce Sulfhydryl Addition Kit contains all necessary components to introduce free sulfhydryl groups into any primary amine-containing molecule, purify the modified molecule and quantify the added sulfhydryl groups. SATA is a short-chain (2.8 angstrom spacer arm) reagent for covalent modification of primary amines and addition of a protected yet exposable sulfhydryl group, enabling heterobifunctional crosslinking strategies.
Features
- Adds a protected sulfhydryl that can be deprotected by hydroxylamine
- Allows long-term storage of the sulfhydryl-modified molecule
- Forms cleavable disulfide bonds with other sulfhydryl-containing molecules
- Reacts with primary amines (e.g., lysine residues proteins) to form stable amide bonds
- Preserves protein activity with its mild, non-denaturing reaction conditions
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