Thermo Scientific™ MT(PEG)4 Methyl-PEG-Thiol Compound

Thermo Scientific™ MT(PEG)4 Methyl-PEG-Thiol Compound

Thermo Scientific Pierce MT(PEG)4, or methyl-PEG4-thiol, is a methyl- and sulfhydryl-terminated compound that contains a 4-unit polyethylene glycol (PEG) spacer and is used to modify surfaces such as quantum dots, monolayers and magnetic particles.

MT(PEG)4 is monodentate thiol-terminated and methyl pegylation reagent. The PEG compound has a defined molecular weight and spacer length and is useful for modifying surfaces such quantum dots, self-assembled monolayers and magnetic particles. Functionalization of solid surfaces with polyethylene glycol spacers such as this one significantly reduces nonspecific protein binding.

Features

• Metal-binding—terminal monodentate thiol reacts spontaneously with gold surfaces through dative binding
• Methyl—terminal methyl group is unreactive, the primary function of this compound being to coat quantum dot and other surfaces to reduce nonspecific binding in assays
• Polyethylene glycol—PEG groups are flexible, non-immunogenic, hydrophilic, and significantly reduce nonspecific binding of surfaces for protein methods
• Spacer arm—four-unit PEG spacer makes compound nearly 16 angstroms long