Thermo Scientific™ ML(PEG)4 Methyl-PEG-Lipoamide Compound

Thermo Scientific™ ML(PEG)4 Methyl-PEG-Lipoamide Compound

Thermo Scientific Pierce ML(PEG)4, or methyl-PEG4-lipoamide, is a methyl- and bidentate thiol-terminated compound that contains a 4-unit polyethylene glycol (PEG) spacer and is used to modify quantum dots, silver and gold surfaces and magnetic particles.

ML(PEG)4 is a bidentate thiol-terminated and carboxylic acid pegylation reagent. The PEG compound has a defined molecular weight and spacer length and is useful for modifying surfaces such quantum dots, self-assembled monolayers and magnetic particles. Functionalization of solid surfaces with polyethylene glycol spacers such as this one significantly reduces nonspecific protein binding.

Features

• Metal-binding—terminal bidentate thiol reacts spontaneously with silver, gold and other metal surfaces to form strong dative bonds
• Methyl—terminal methyl group is unreactive, the primary function of this compound being to coat quantum dot and other surfaces to reduce nonspecific binding in assays
• Polyethylene glycol—PEG groups are flexible, non-immunogenic, hydrophilic, and significantly reduce nonspecific binding of surfaces for protein methods
• Spacer arm—four-unit PEG spacer makes compound nearly 24 angstroms long