Thermo Scientific™ Pierce™ Protein L Plus Agarose

Thermo Scientific™ Pierce™ Protein L Plus Agarose

Thermo Scientific Pierce Protein L Plus Agarose is a high-capacity Protein L beaded agarose resin for use in a variety of antibody affinity purification methods.

Pierce Protein L Plus Agarose is a high-capacity affinity resin for purification of mammalian IgG isotypes that contain specific kappa light chains. Protein L is especially suited for isolating mouse IgG VkI and human IgG VkI, VkIII and VkIV monoclonal antibodies. The resin consists of recombinant Protein L immobilized on crosslinked 6% beaded agarose (CL-6B) using a stable, leach-resistant chemistry. The agarose beads can be regenerated and reused multiple times when stored properly.

Features

• Protein L – immobilized Protein L is ideal for selective purification of human and mouse antibodies that have kappa light chains
• Agarose resin – support is crosslinked 6% beaded agarose (CL-6B), the most popular resin for protein affinity purification methods
• Inert and stable – superior manufacturing method immobilizes Protein L by charge-free, leach-resistant covalent bonds, resulting in low nonspecific binding and enabling multiple uses without decline in yield
• High capacity – this “Plus” variety of Pierce Protein L Agarose has a dense load of immobilized Protein L, providing a binding capacity of 10 to 20 mg human IgG/mL resin