Invitrogen™ LentiArray™ Human GPCR CRISPR Library

Invitrogen™ LentiArray™ Human GPCR CRISPR Library

The award-winning Invitrogen™ LentiArray™ Human GPCR Library targets 446 genes with up to 4 gRNA per gene target (pooled in a single well) for a total of 1,784 gRNAs. Libraries are delivered as 100 μL of ready to use lentiviral particles per gene target with an average titer of 1x108 TU/mL (functional titer determined by antibiotic resistance) and are also available as glycerol stocks.

G protein-coupled receptors (GPCRs) are regulators of a wide range of physiological and disease processes. GPCRs have emerged as one of the most druggable classes of genes, with nearly 30% of FDA approved drugs targeting GPCRs. The gene targets within this library were selected using the most up-to-date genome databases, including the NCBI RefSeq database, and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC).

Contents

• 1 library set, 100 µL/target