Invitrogen™ Silencer™ Select Human Cancer Genome siRNA Library

Invitrogen™ Silencer™ Select Human Cancer Genome siRNA Library

The Silencer™ Select Human Cancer Genome siRNA Library contains 1596 Ambion™ Silencer Select siRNAs targeting 532 gene targets that are commonly affected in cancers. This library of highly potent, chemically-modified siRNAs was designed using the most up-to-date genome databases, including the NCBI RefSeq database and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC) as well as The Cancer Genome Atlas (TCGA). The Silencer Select siRNAs are designed using Thermo Fisher Scientific’s leading algorithms—along with our novel locked nucleic acid (LNA) chemical modifications, this helps to maximize the efficacy, specificity and potency required for RNAi functional screening against cancer gene targets.

Features

• Superior efficacy—Reduce off target effects by up to 90% due to latest design algorithms and LNA chemical modifications
• Highest efficiency—Perform knockdown studies with 100-fold more potent siRNAs than currently available siRNAs
• Dependable—Achieve faster discoveries via consistency of gene knockdown and reliability of phenotypic results
• Convenient—Reduce data de-convolution and accelerate target validation with our arrayed format
• Customizable—Choose the best option for your workflow demands, including additional siRNA scales and pooled formats

Contents

• 1596 total siRNAs targeting 532 genes plated onto 96-well plates (21 plates)