MPL W515L/K, (PCR)
On demand
Order number :
ON-P15
MPL W515L and MPL W515K mutations
Main indication:
MPD.
Test usage:
MPL gene mutations occur in cases of primary myelofibrosis (PMF) and essential thrombocythemia (ET) at a frequency of ~10% and 3% respectively. Testing for MPL mutations may aid in the diagnosis of these myeloproliferative neoplasms. MPL mutations are usually found in cases that test negative for the JAK2 V617F mutation, although a small number of patients have been reported with both mutations.
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