EGFR (30 mutations), (PCR)

Detection of the most common 30 EGFR mutations in Exons 18-19-20 and 21 

Main indication:

NSCLC.

Test usage:

Mutations affecting EGFR occur in approximately 10-20% of non-small cell lung cancers (NSCLC). The particular mutation(s) present within neoplastic cells affects the predicted response to specific targeted therapies including EGFR-directed treatments. This DNA test is performed by targeted next-generation sequencing (NGS) and will detect EGFR mutations within the sequenced regions of exons 3, 7, 12, 15, and 18-21. Specimens should contain an adequate proportion of neoplastic cells (>20%) in the area to be extracted to ensure mutation detection.