Thermo Scientific™ GMBS (N-γ-maleimidobutyryl-oxysuccinimide ester)
On demand
Order number :
22309
Thermo Scientific™ GMBS (N-γ-maleimidobutyryl-oxysuccinimide ester)
Thermo Scientific Pierce GMBS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a short spacer arm (7.3 angstroms).
Features
- Reactive groups: NHS ester and maleimide
- Reactive toward: amino and sulfhydryl groups
- C4-homolog of aliphatic spacer series which includes AMAS, BMPS, GMBS and EMCS
- NHS ester end couples with primary amines at pH 7-9 to form stable amide bonds
- Maleimides react with -SH groups at pH 6.5-7.5, forming stable thioether linkages
- Non-cleavable
- Water-insoluble (dissolve first in DMF or DMSO); compare to Sulfo-GMBS
- Short aliphatic spacer has low potential for eliciting an immune response
There are no specifications
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