Thermo Scientific™ Pierce™ EMCA (N-ε-maleimidocaproic acid)

Thermo Scientific™ Pierce™ EMCA (N-ε-maleimidocaproic acid)

Thermo Scientific Pierce EMCA is a carboxylic acid compound with a terminal maleimide group that can modify proteins and other molecules by EDC-mediated and sulfhydryl-targeted conjugation.

Features

• Convert sulfhydryl groups to carboxyl groups for conjugation to amines via carbodiimide (EDC)
• Prepare maleimide-activated proteins using EDC to modify primary amines
• Maleimides react with—SH groups at pH 6.5-7.5, forming stable thioether linkages