Thermo Scientific™ PMPI (p-maleimidophenyl isocyanate)
On demand
Order number :
28100
Thermo Scientific™ PMPI (p-maleimidophenyl isocyanate)
Thermo Scientific Pierce PMPI is a maleimide-and-isocyanate crosslinker for attaching compounds to sulfhydryl groups (cysteines) after conjugating the linker to hydroxyl groups on a molecule by urethane (carbamate) bonds.
Features
- Reactive groups: maleimide and isocyanate
- Reactive towards: sulfhydryl and hydroxyl groups
- Short (8.7A), sulfhydryl-to-hydroxyl crosslinker with an aromatic spacer arm (noncleavable)
- Maleimide group reacts with sulfhydryl groups to form stable thioether linkages
- Isocyanate reacts with non-aqueous hydroxyl groups to form carbamate linkage
- Excellent tool for conjugating hydroxyl-containing compounds such as steroids and vitamins
- Targets and reaction solutions must not contain primary amines
There are no specifications
There are no report
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