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NRAS, (PCR)

On demand
Order number : ON-P09
(Ex-work price)
$ On demand

Detection of the most common 22 NRAS mutations in codons 12, 13, 59, 60 and 61  


Main indication:

CRC.


Test usage:

Activating mutations in the NRAS gene occur in approximately 2-3% of colorectal carcinomas, 20% of melanomas, and a variety of other human cancers. NRAS mutations are predominantly single nucleotide substitutions, occurring most frequently within exons 2 and 3 at codons 12, 13, and 61. These NRAS mutations are associated with poor clinical response to epidermal growth factor receptor (EGFR) targeted therapies in patients with colorectal cancer.

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