Thermo Scientific™ SureQuant™ AKT Isoform Relative Quantitation Module

Thermo Scientific™ SureQuant™ AKT Isoform Relative Quantitation Module

The Thermo Scientific SureQuant AKT Isoform Relative Quantitation Module provides a complete quantitation solution for the analysis of key AKT expression using mass spectrometry (MS).

The AKT signaling pathway serves as a master regulatory pathway for cell growth and proliferation, and AKT plays a vital role in the signaling cascade. Aberrant activation of this pathway promotes survival of tumor cells in many types of cancer. This kit is ideal for monitoring AKT expression levels of the three isoforms and phosphorylation status in a single assay. The ability to simultaneously monitor and quantitate in a single sample is a powerful tool for assessment of normal and abnormal pathway signaling.

For use with: Thermo Scientific™ Q Exactive Mass Spectrometer, Mass Spectrometer

Features

• Complete—contains validated AQUA HeavyPeptide mix, diluent, matrix, system suitability standard including optimized acquisition and analysis methods
• Validated—peptides rigorously tested for successful quantitation of each target peptide
• Multiplex—able to quantitate AKT1, AKT2, and AKT3 isoforms and phosphorylation of AKT