Thermo Scientific™ SureQuant™ TP53 Panel Relative Quantitation Module

Thermo Scientific™ SureQuant™ TP53 Panel Relative Quantitation Module

The Thermo Scientific SureQuant TP53 Panel Relative Quantitation Module provides a complete quantitation solution for the analysis of key TP53 expression and phosphorylation using mass spectrometry (MS).

The tumor suppressor protein TP53 functions as a negative checkpoint regulator for abnormal cell signaling and can induce cell cycle arrest, activate DNA repair proteins, or initiate apoptosis. Mutations in TP53 often result abnormal cell growth and are commonly found in many types of cancer. This kit is ideal for monitoring TP53 expression and phosphorylation status in a single assay. The ability to simultaneously monitor and quantitate in a single sample is a powerful tool for assessment of normal and abnormal pathway signaling.

For use with: Thermo Scientific™ Q Exactive Mass Spectrometer, Mass Spectrometer

Features

• Complete—contains validated AQUA HeavyPeptide mix, diluent, matrix, and system suitability standard including optimized acquisition and analysis methods
• Validated—peptides rigorously tested for successful quantitation of each target peptide
• Multiplex—able to quantitate NRAS, KRAS, and HRAS isoforms